New York: Former US President Ronald Reagan has died at the age of 93 after a decade-long struggle with Alzheimer's disease, his office and family sources said.

Reagan, a two-term President and former Hollywood star, died at his home in Los Angeles shortly before 14:00 hours local time (02:30 hours IST on Sunday).

Reagan's wife Nancy said in a statement, "My family and I would like the world to know that president Ronald Reagan has passed away after 10 years of Alzheimer's at 93. We appreciate everyone's prayers over the years."

"Ron and Patti are with him," said Reagan family chief of staff Joanne Drake after the White House was informed that the 40th US President's health had declined and that the end of his life could be near.

The US leader known as the "Great Communicator", who served as President from 1981-1989, was the longest-living US President in history, despite narrowly escaping death in a 1981 assassination attempt in Washington.