'Gum disease may increase pancreatic cancer risk' Wednesday, January 17, 2007 04:48 [IST]
New York:
"People suffering from gum disease are likely to face the risk of
developing cancer of the pancreas, an organ in the digestive system, and the
worse the gum disease, the higher the risk," says a study.
Gum disease is a common dental problem that may result in
tooth loss.
Dominique S. Michaud, Sc.D., along with colleagues at the
Harvard School of Public Health, US, analysed data from 51,529 male health
professionals a large number of whom were non-smokers who were followed for 16 years.
Michaud's team found that, overall, study subjects who
reported gum disease were 64 per cent more likely to have pancreatic cancer,
reported online edition of health magazine WebMD.
Among non-smokers, those with gum disease were more than
twice as likely to have pancreatic cancer, the researchers said. The risk is
more in people who lost tooth due to disease.
People with a history of gum disease, recent tooth loss,
have a 2.7-fold higher risk of this fatal cancer than people without gum
disease or tooth loss, according to the finding appeared in the Jan 17 issue of
the Journal of the National Cancer Institute.
Previous studies have linked gum disease to pancreatic
cancer. But those studies could not control for smoking, which contributes to
both gum disease and cancer.
Although it is not clear why gum disease is linked to cancer
risk, the researchers suggest that long-standing gum infections trigger a
body-wide immune response: inflammation. Inflamed tissues give off chemical
signals that promote tumour growth.
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